References

Selected publications of group members

2017

  • Vergunst Ac, Lopez Carranza N, Zhang L, Gomes MC, Tasrini Y, Meijer AH, O’Callaghan D (2017). Macrophages as drivers of an opportunistic infection. Microbial cell. In press.
  • Mesureur J, Feliciano-Rodrigues J, Wagner N, Zhang L, Gomes, M, Blanco M, van der Vaart M, O’Callaghan D, Meijer AH, Vergunst A. (2017) Macrophages, but not neutrophils, are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation. PLoS Pathog 13(6): e1006437 full text
  • Ngba Essebe C, Visvikis O, Fines-Guyon M, Vergne A, Cattoir V, Lecoustumier A, Lemichez E, Sotto A, Lavigne JP, Dunyach-Remy C. Decrease of Staphylococcus aureus Virulence by Helcococcus kunzii in a Caenorhabditis elegans Model. Front Cell Infect Microbiol. 2017 Mar 16;7:77. full text
  • Abderrahim A, Djahmi N, Pujol C, Nedjai S, Bentakouk MC, Kirane-Gacemi D, Dekhil M, Sotto A, Lavigne JP, Pantel A. First Case of NDM-1-Producing Klebsiella pneumoniae in Annaba University Hospital, Algeria. Microb Drug Resist. 2017 Feb 22. doi: 10.1089/mdr.2016.0213. [Epub ahead of print] abstract
  • Agnoli K, Freitaga R, Gomes M, Jenul C, Suppinger A, Mannweiler O, Frauenknecht C, Janser D, Vergunst A, and Eberl L. (2017). The use of synthetic hybrid strains to determine the role of replicon 3 in virulence of the Burkholderia cepacia Appl Environ Microbiol. doi: 10.1128/AEM.00461-17. [Epub ahead of print] Abstract
  • Rasigade JP, Dunyach-Rémy C, Sapin A, Messad N, Trouillet-Assant S, Dupieux C, Lavigne JP, Laurent F. A Prophage in Diabetic Foot Ulcer-Colonizing Staphylococcus aureus Impairs Invasiveness by Limiting Intracellular Growth. J Infect Dis.15;214(10):1605-1608.
  • Dunyach-Remy C, Courtais-Coulon C, DeMattei C, Jourdan N, Schuldiner S, Sultan A, Carrière C, Alonso S, Sotto A, Lavigne JP. Link between nasal carriage of Staphylococcus aureus and infected diabetic foot ulcers. Diabetes Metab. 43(2):167-171. Abstract

2016

  • Soler-Lloréns PF, Quance CR, Lawhon SD, Stuber TP, Edwards JF, Ficht TA, Robbe-Austerman S, O’Callaghan D, Keriel A. A Brucella spp. Isolate from a Pac-Man Frog (Ceratophrys ornata) Reveals Characteristics Departing from Classical Brucellae. Front Cell Infect Microbiol. 6: 116. full text
  • Garcia-Mendez K.G., Bragagnolo G., O’Callaghan D., Lavigne J-P. and Keriel A. A high-throughput assay for the measurement of uropathogenic Escherichia coli attachment to urinary bladder cells. Int. J. Exp. Pathol. 97(2):194-201 full text
  • Pantel A, Dunyach-Remy C, Ngba Essebe C, Mesureur J, Sotto A, Pagès JM, Nicolas Chanoine MH, Lavigne JP. Modulation of membrane influx and efflux in Escherichia coli ST131 has an impact on bacterial motility, biofilm formation and virulence in a Caenorhabditis elegans model. Antimicrob Agents Chemother. 2016;60(5):2901-11.
  • Brahmi S, Touati A, Cadière A, Djahmi N, Pantel A, Sotto A, Lavigne JP, Dunyach-Remy C. First description of two OXA-23-mediated carbapenem resistance in Sequence Type 2 Acinetobacter baumannii isolates in Pagellus acarne fished in the Mediterranean Sea afar Bejaia (Algeria). Antimicrob Agents Chemother. 2016 ;60(4):2513-5.
  • Fernández-González E, Bakioui S, Gomes, M, O´Callaghan D, Vergunst AC, Sangari FJ and Llosa M. (2016) A functional oriT in the Ptw plasmid of Burkholderia cenocepacia can be recognized by the R388 relaxase TrwC. Front. Mol. Biosci., full text
  • Mesureur J, Ranaldi S, Monnin V, Girard V, Arend S, Welker M, O’Callaghan D, Lavigne JP, Keriel A. (2016) A Simple and Safe Protocol for Preparing Brucella Samples for Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Analysis. J Clin Microbiol. 2016 Feb;54(2):449-52.text

2015

  • Keriel A, Botella E, Estrach S, Bragagnolo G, Vergunst AC, Feral CC, O’Callaghan D. Brucella relies on the transmembrane protein CD98 heavy chain for its intracellular replication.J Infect Dis. 211 (11): 1769-1778 doi:10.1093/infdis/jiu673 full text
  • Saadeh B, Caswell CC, Chao Y, Berta P, Wattam AR, Roop RM 2nd, O’Callaghan D.Transcriptome-Wide Identification of Hfq-Associated RNAs in Brucella suis by Deep Sequencing. J Bacteriol. 2015 Nov 9;198(3):427-35. doi: 10.1128/JB.00711-15.
  • Brahmi S, Dunyach-Remy C, Touati A, Lavigne JP. CTX-M-15-producing extraintestinal pathogenic Escherichia coli belonging to O25b-ST131 clone isolated from wild fish in Mediterranean Sea. Clin Microbiol Infect 2015;21(3):e18-20.
  • Messad N, Prasjnar TK, Lina G, O’Callaghan D, Foster SJ, Renshaw SA, Skaar EP, Benito Y, Dunyach-Remy C, Vandenesch F, Sotto A, Lavigne JP. Existence of a colonizing Staphylococcus aureus strain isolated in diabetic foot ulcers. Diabetes. 2015;64(8):2991-5.

 2014

  • Brahmi S, Dunyach-Remy C, Touati A, Lavigne JP. CTX-M-15-producing extraintestinal pathogenic Escherichia coli belonging to O25b-ST131 clone isolated from wild fish in Mediterranean Sea. Clin Microbiol Infect. In press
  • Bialek S, Lavigne JP, Guyot K, Mayer N, Tournebize R, Brisse S, Leflon-Guibout V, Nicolas-Chanoine MH. Differential contribution of AcrAB and OqxAB efflux pumps to multidrug resistance and virulence in Klebsiella pneumoniae. J Antimicrob Chemother.
  • Liapis E, Pantel A, Robert J, Nicolas-Chanoine MH, Cavalié L, van der mee-Marquet N, de Champs C, Aissa N, Eloy C, Blanc V, Guyeux C, Hocquet D,  Lavigne JP, Bertrand X on behalf of ONERBA. Molecular epidemiology of OXA-48-producing Klebsiella pneumoniae in France. Clin Microbiol Infect. doi: 10.1111/1469-0691.12727.
  • Felix C, Kaplan Türköz B, Ranaldi S, Koelblen T, Terradot L, O’Callaghan D, Vergunst AC. The Brucella TIR domain containing proteins BtpA and BtpB have a structural WxxxE motif important for protection against microtubule depolymerisation. Cell Comm Sign. 12:53. doi: 10.1186/s12964-014-0053-y.53  full text
  • Robert J, Pantel A, Mérens A, Lavigne JP, Nicolas-Chanoine MH; on behalf of ONERBA’s Carbapenem Resistance Study Group. Incidence rates of carbapenemase-producing Enterobacteriaceae clinical isolates in France: a prospective nationwide study in 2011-12. J Antimicrob Chemother. 69(10) : 2706-12.
  • Vergunst AC and O’Callaghan D. Host bacteria interactions. Volume series in Methods in Molecular Biology. link
  • Mesureur J, Vergunst AC. (2014) Zebrafish embryos as a model to study bacterial virulence. Methods Mol Biol 1197:41-66.  doi: 10.1007/978-1-4939-1261-2_3 abstract
  • Dunyach-Remy C, Cadière A, Richard JL, Schuldiner S, Bayle S, Roig B, Sotto A, Lavigne JP. Denatured gradient gel electrophoresis: a promising tool to diagnose bacterial infections in diabetic foot ulcers. Diabet Metabolism. doi: 10.1016/j.diabet.2014.03.002.
  • Pantel A, Boutet-Dubois A, Jean-Pierre H, Marchandin H, Sotto A, Lavigne JP, and CARB-LR group. French Regional surveillance program of carbapenemase-producing Gram-negative bacilli: Result of two-years period. Eur J Clin Microbiol Infect Dis. 33(12):2285-92
  • Agabou A, Pantel A, Ouchenane Z, Lezzar N, Khemissi S, Satta D, Sotto A, Lavigne JP. First description of OXA-48-producing Escherichia coli and the pandemic clone ST131 from patients hospitalised at a military hospital in Algeria. Eur J Clin Microbiol Infect Dis. 33(9): 1641-6
  • Senneville E, Brière M, Neut C, Messad N, Lina G, Richard JL, Sotto A, Lavigne JP; The French Study Group on the Diabetic Foot. irst report of the predominance of clonal complex 398 Staphylococcus aureus strains in osteomyelitis complicating diabetic foot ulcers: a national French study. Clin Microbiol Infect.: 20(4) : O274-7
  • Berta P, Bourg G, Hanna N, Saadeh B, Armengaud J, Patey G, O’Callaghan D.  The Brucella suis IbpA heat-shock chaperone is not required for virulence or for expression of the VirB type IV secretion system VirB8 protein. Lett Appl Microbiol. 58(6):564-8  pdf
  • Wattam AR, Foster JT, Mane SP, Beckstrom-Sternberg SM, Beckstrom-Sternberg JM, Dickerman AW, Keim P, Pearson T, Shukla M, Ward DV, Williams KP, Sobral BW, Tsolis RM, Whatmore AM, O’Callaghan D. Comparative phylogenomics and evolution of the brucellae: A path to virulence. J.Bact.196(5):920-30 pdf
  • Agnoli K, Frauenknecht C, Freitag R, Schwager S, Vergunst A, Jenul C, Carlier A, and Eberl L. The third replicon of members of the Burkholderia cepacia complex, plasmid pC3, plays a role in stress tolerance. Appl Environ Microbiol. February 2014 vol. 80 no. 4 1340-1348 abstract

2013

  • Kaplan-Türköz B, Koelblen T, Felix C, Candusso MP, O’Callaghan D, Vergunst AC, Terradot L. Structure of the Toll/interleukin 1 receptor (TIR) domain of the immunosuppressive Brucella effector BtpA/Btp1/TcpB. FEBS Lett. 587: 3412-3416 pdf
  • O’Callaghan D. Novel replication profiles of Brucella in human trophoblasts give insights into the pathogenesis of infectious abortion. J Infect Dis. 207(7):1034-6.
  • Senneville E, Brière M, Neut C, Messad N, Lina G, Richard JL, Sotto A, Lavigne JP. The French Study Group on the Diabetic Foot. First report of the predominance of clonal complex 398 Staphylococcus aureus strains in osteomyelitis complicating diabetic foot ulcers: a national French study. Clin Microbiol Infect. .
  • Psomas C, Lavigne JP, Barbuat C, Trabelsi S, Ghosn J, Lascoux-Combe C, Flandre P, Cuzin L, Reynes J, Autran B, Corbeau P. Maraviroc-induced decrease in circulating bacterial products is not linked to an increase in immune activation in HIV-infected individuals. Blood. 22(13):2282-3.
  • Chevalier MF, Petitjean G, Dunyach-Rémy C, Didier C, Girard PM, Manea ME, Campa P, Meyer L, Rouzioux C, Lavigne JP, Barré-Sinoussi F, Scott-Algara D, Weiss L. The Th17/Treg ratio, IL-1RA and sCD14 levels in primary HIV infection predict the T-cell activation set point in the absence of systemic microbial translocation. PLoS Pathog. 9(6):e1003453.
  • Lavigne JP, Audibert S, Molinari N, O’Callaghan D, Keriel A. Influence of a high-glucose diet on the sensitivity of Caenorhabditis elegans towards Escherichia coli and Staphylococcus aureus strains. Microbes Infect. 15:540-9. Abstract
  • Djahmi N, Messad N, Nedjai S, Moussaoui A, Mazouz D, Richard JL, Sotto A, Lavigne JP. Molecular epidemiology of Staphylococcus aureus strains isolated from patients with infected diabetic foot ulcers in an Algerian University Hospital. Clin Microbiol Infect. Feb 26. doi: 10.1111/1469-0691.12199. pdf
  • Lavigne JP, Cuzon G, Combescure C, Bourg G, Sotto A, Nordmann P. Virulence of Klebsiella pneumoniae Isolates Harboring bla KPC-2 Carbapenemase Gene in a Caenorhabditis elegans Model. PLoS One; 8(7):e67847. doi: 10.1371/journal.pone.0067847. pdf
  • Boutet-Dubois A, Pantel A, Prère MF, Bellon O, Brieu-Roche N, Lecaillon E, Le Coustumier A, Davin-Regli A, Villeneuve L, Bouziges N, Gleize E, Lamarca R, Dunyach-Remy C, Sotto A, Lavigne JP. Faecal carriage of oxyiminocephalosporin-resistant Enterobacteriaceae among paediatric units in different hospitals in the south of France. Eur J Clin Microbiol Infect Dis.; 32(8):1063-8. Abstract
  • Lipsky BA, Richard JL, Lavigne JP. Diabetic foot ulcer microbiome: one small step for molecular microbiology . . . One giant leap for understanding diabetic foot ulcers? Diabetes.;62(3):679-81. Abstract

2012

  • Yumuk Z, O’Callaghan D. Brucellosis in Turkey — an overview. Int J Infect Dis. 2012 Apr;16(4):e228-35. doi: 10.1016/j.ijid.2011.12.0.11 pdf
  • Sprynski N, Felix C, O’Callaghan D, Vergunst AC. Restoring virulence to mutants lacking subunits of multiprotein machines; functional complementation of a Brucella virB5 mutant. FEBS open Bio 2: 71-75. abstract
  • Lavigne J, Vergunst AC, Goret L, Sotto A, Combescure C, Blanco6 J, O’Callaghan D, Nicolas-Chanoine M. Virulence Potential and Genomic Mapping of the Worldwide Clone Escherichia coli ST131. Plos One, 10.1371/journal.pone.0034294  pdf
  • Agnoli K, Schwager S, Uehlinger S, Vergunst A, Viteri DF, Nguyen DT, Sokol PA, Carlier A, Eberl L. Exposing the third chromosome of Burkholderia cepacia complex strains as a virulence plasmid. Mol Micro. 83: 362-378 pubmed
  • Sotto A, Richard JL, Messad N, Molinari N, Jourdan N, Schuldiner S, Sultan A, Carrière C, Canivet B, Landraud L, Lina G, Lavigne JP, the French Study Group on the Diabetic Foot. Distinguishing colonization from infection with Staphylococcus aureus in diabetic foot ulcers with miniaturized oligonucleotide arrays: a French multicenter study. Diabetes Care. 2012 Feb 1. pubmed
  • Richard JL, Lavigne JP, Sotto A. Diabetes and foot infection: more than double trouble. Diabetes Metab Res Rev. Feb; 28(S1): 46-53. pubmed

2011

  • Richard JL, Lavigne JP, Got I, Hartemann A, Malgrange D, Tsirtsikolou D, Baleydier A, Senneville E. Management of patients hospitalized for diabetic foot infection: results of the French OPIDIA study. Diabetes Metab. 37(3):208-15.
  • O’Callaghan D, Whatmore AM Brucella genomics as we enter the multi-genome era.Brief Funct Genomics. 10(6):334-41.
  • Andrieux L, Bourg G, Pirone A, O’Callaghan D, Patey G. A single amino acid change in the transmembrane domain of the VirB8 protein affects dimerization, interaction with VirB10 and Brucella suis virulence. FEBS Lett;585(15):2431-6
  • El Habnouni S, Darcos V, Garric X, Lavigne JP, Notellet B, Coudane J. Mild Methodology for the Versatile Chemical Modification of Polylactide Surfaces: Original Combination of Anionic and Click Chemistry for Biomedical Applications. Adv Funct Mater.  [Epub ahead of print]
  • Lavigne JP, Boutet-Dubois A, Laouini D, Combescure C, Bouziges N, Marès P, Sotto A. Virulence potential of Escherichia coli strains causing asymptomatic bacteriuria during pregnancy. J Clin Microbiol. 49(11):3950-3.
  • Lavigne JP, Sotto A, Nicolas-Chanoine MH, Bouziges N, Bourg G, Davin-Regli A, Pagès JM. Membrane permeability, a pivotal function involved in antibiotic resistance and virulence in Enterobacter aerogenes clinical isolates. Clin Microbiol Infect. 18(6):539-45

2010

  • O’Callaghan D, Vergunst A (2010) Non-mammalian animal models to study infectious disease: worms or fly fishing? Curr Opinion Microbiol 13 : 79-85
  • Vergunst AC, Meijer AH, Renshaw SA, O’Callaghan D (2010) Burkholderia cenocepacia creates an intra-macrophage replication niche in zebrafish embryos, followed by bacterial dissemination and establishment of systemic infection.  Infect Immun. 78: 1495-1508
  • O’Callaghan D, Stebbins CE. (2010) Host-microbe interactions: bacteria. Curr Opin Microbiol. 2010 Feb;13(1):1-3.

2009

  • Amalric J, Mutin PH, Guerrero G, Ponche A, Sotto A, Lavigne PH Phosphonate monolayers functionalized by silver thiolate species as antibacterial nanocoating on titanium and stainless steel. J. Mater Chem. 19: 141-149
  • Bourg G, Sube R, O’Callaghan D Patey G. Interactions between  Brucella suis VirB8 and its homolog TraJ from the plasmid pSB102 underline the dynamic nature of type IV secretion systems.  J Bacteriol 191, 2985-2992
  • Martin FA, Posadas DM, Carrica MC, Cravero SL, O’Callaghan D, Zorreguieta A Interplay between two RND systems mediating antimicrobial resistance in  Brucella suis .  J Bacteriol 191, 2530-2540.

2008

  • Alix E, Blanc-Potard AB Peptide-assisted degradation of the Salmonella MgtC virulence factor. EMBO J 27, 546-557.
  • Jeandrot A, Richard JL, Combescure C, Jourdan N, Finge S, Rodier M, Corbeau P, Sotto A, Lavigne JP. Serum PCT and CRP concentrations to discriminate mildly infected from non-infected diabetic foot ulcer: a pilot study. Diabetologia 51(2):347-352.
  • Lavigne JP, Bourg G, Combescure C, Botto H, Sotto A.  In vitro and in vivo evidences of dose-dependent decrease of uropathogen Escherichia coli virulence after consumption of Vaccinium macrocarpon cranberry (Urell®). Clin Microbiol Inf 14(4):350-5.
  • Lavigne JP, Nicolas-Chanoine MH, Bourg G, Moreau J, Sotto A. Virulent synergistic effect between Enterococcus faecalis and Escherichia coli assayed by using the Caenorhabditis elegans model. PLoS One 3(10):e3370.
  • Nicolas-Chanoine MH, Blanco J, Leflon-Guibout V, Demarty R, Alonso MP, Caniça MM, Park YJ, Lavigne JP, Pitout J, Johnson JR. Intercontinental emergence of Escherichia coli clone O25:H4-ST131 producing CTX-M-15. J Antimicrob Chemother 61(2):   273-281. Richard JL, Sotto A, Jourdan N, Combescure C, Vannereau D, Rodier M, Lavigne JP. Risk factors for and impact on healing of multidrug-resistant bacteria in diabetic foot ulcers. Diabetes Metab 34: 363-369.
  • Sotto A, lina G, Richard JL, Combescure C, Bourg G, Vidal L, Jourdan N, Etienne J, Lavigne JP. Virulence potential of Staphylococcus aureus strains isolated from diabetic foot ulcers: a new paradigm. Diabetes Care 31: 2318-24
  • Yumuk Z, Afacan G, Nicolas-Chanoine MH, Sotto A, Lavigne JP. Turkey: a further country concerned by community-acquired Escherichia coli clone O25-ST131 producing CTX-M-15. J Antimicrob Chemother 62(2):284-8.

2007

  • Alix E and Blanc-Potard AB. MgtC: a key player in intramacrophage survival. Trends Microbiol. 15: 252-256
  • Angot A*, Vergunst A*, Genin and Peeters N. Exploitation of eukaryotic ubiquitin signaling pathways by effectors translocated by bacterial type III and type IV secretion systems. PLos Path 3 (1), e3 1-13, *equal contribution
  • Bourg G, O’Callaghan D, Boschiroli ML. The genomic structure of Brucella strains isolated from marine mammals gives clues to evolutionary history within the genus. Vet Microbiol 125: 375-380
  • Lavigne JP, Marchandin H, Delmas J, Moreau J, Bouziges N, Lecaillon E, Cavalie L, Jean-Pierre H, Bonnet E, Sotto A. CTX-M-beta-lactamase-producing  Escherichia coli in French hospitals: prevalence, molecular epidemiology, and risk factors. J. Clin Microbiol 45: 620-626
  • Sotto A, Richard JL, Jourdan N, Combescure C, Bouziges N, Lavigne JP. Miniaturized oligonucleotide arrays: a new tool for discriminating colonization from infection due to Staphylococcus aureus in diabetic foot ulcers. Diabetes Care 30: 2051-2056

2006

  • Carle A, Höppner C, Aly KA, Yuan Q, den Dulk-Ras A, Vergunst A, O’ Callaghan D, Baron C. The Brucella suis type IV secretion system assembles in the cell envelope of the heterologous host Agrobacterium tumefaciens and increases IncQ plasmid pLS1 recipient competence. Infect Immun 74: 108-117
  • Lavigne JP, Blanc-Potard AB, Bourg G, Moreau J, Chanal C, Bouziges N, O’Callaghan D, Sotto A. Virulence genotype and nematode-killing properties of extra-intestinal Escherichia coli producing CTX-M beta-lactamases. Clin Microbiol Infect. 12(12): 1199-206.
  • Lavigne JP, Marchandin H, Delmas J, Bouziges N, Lecaillon E, JeanPierre H, Cavallie L, Bonnet R and Sotto A. qnrA in CTX-M-producing Escherichia coli isolates from France.  Antimicrob Agents Chemother. 50: 4224-4228
  • Paschos A*, Patey G*, Sivanesan D, Gao C, Bayliss R, Waksman G, O’Callaghan D, Baron C. Dimerization and interactions of Brucella suis VirB8 with VirB4 and VirB10 are required for its biological activity. Proc. Natl. Acad. Sci. U. S. A 103: 7252-7, *equal contribution
  • Patey G, Zhong Q, Bourg G, Baron C and O’Callaghan D. Domain swapping of periplasmic domains between Brucella suis and pSB102 VirB8 proteins allow heterologous complementation. Infect Immun. 74(8): 4945-4949
  • Rang C, Alix E, Felix C, Heitz A, Tasse L, and Blanc-Potard A-B. Dual role of the MgtC virulence factor in host and non-host environments. Mol. Microbiol. 63:605-623

2005

  • Lavigne JP, Vergunst AC, Bourg G and O’Callaghan D. The IncP island in the genome of Brucella suis 1330 was acquired by site-specific integration.  Infect Immun 73:7779-7783
  • Vergunst, AC, van Lier MC, den Dulk-Ras A, Grosse Stuve TA, Ouwehand A and Hooykaas PJJ. Positive charge is an important feature of the C-terminal transport signal of the VirB/D4-translocated proteins of Agrobacterium. PNAS 102:832-837

2004

  • Batut J, Andersson SG and O’Callaghan D. The evolution of chronic infection strategies in the alpha-proteobacteria. Nat Rev Microbiol. 2:933-945

2002

  • Boschiroli ML, Ouahrani-Bettache S, Foulonge V, Michaux-Charachon S, Bourg G, Allardet-Servent A, Cazevieille C, Liautard JP, Ramuz M, O’Callaghan D (2002) The Brucella suis virB operon is induced intracellularly in macrophages. PNAS 99 (3): 1544-1549

2000

  • Vergunst AC, Schrammeijer B, den Dulk-Ras A, de Vlaam CMT, Regensburg-Tuink T, Hooykaas PJJ. VirB/D4-dependent protein translocation from Agrobacterium to plant cells. Science 290, 979-982